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6720 Szeged, Korányi fasor 6.

Director: Lajos Kemény MD, DSC,

Head of Department

Laboratory of Molecular Biology

The aim of our research group is to investigate the pathogenesis of immune-mediated, polygenic, multifactorial skin diseases (e.g., psoriasis, acne), commonly occurring in the Hungarian population. We are also interested in studying the interaction between skin cells and various members of the cutaneous microbiome in healthy and pathogenic conditions. Besides these clinically oriented basic research projects we also perform routine clinical diagnostic procedures in our laboratory.

Göblös A, Danis J, Vas K, Bata-Csörgő Z, Kemény L, Széll M. Keratinocytes express functional CARD18, a negative regulator of inflammasome activation, and its altered expression in psoriasis may contribute to disease pathogenesis. Mol Immunol. 2016 May;73:10-8. doi: 10.1016/j.molimm.2016.03.009.

Szabó K, Erdei L, Bolla BS, Tax G, Bíró T, Kemény L. Factors shaping the composition of the cutaneous microbiota. Br J Dermatol. 2017 Feb;176(2):344-351. doi: 10.1111/bjd.14967.

Tax G, Urbán E, Palotás Z, Puskás R, Kónya Z, Bíró T, Kemény L, Szabó K. Propionic Acid Produced by Propionibacterium acnes Strains Contri-butes to Their Pathogenicity. Acta Derm Venereol. 2016 Jan;96(1):43-9. doi: 10.2340/00015555-2154.

Research topics:

  • Investigating the interaction of skin cells and various members of the cutaneous microbiome
  • Studies on Propionibacterium acnes bacterium-induced signalling events in keratinocytes
  • Investigating the effect of the cutaneous microbiome, particularly Propionibacterium acnes on the barrier properties of the skin
  • Psoriasis-related immune- and stress responses of keratinocytes
  • Investigating transcriptional regulatory factors playing a role in the pathogenesis of psoriasis

Routine clinical examinations:

  • Investigation of tissue samples for the detection of autoimmune blistering skin disease (IIF)
  • Bee/wasp allergy etermination (ELISA)
  • Collecting and processing blood samples for Quantiferon analysis
  • Collecting blood samples for clinical examinations
  • Collecting biological samples for the determination of different fungal infections

Staff members:

Lab manager: Kornélia Szabó, PhD senior research fellow, project leader

Beáta Szilvia Bolla, PhD candidate
Judit Danis, PhD candidate
Lilla Erdei, assistant research fellow, PhD candidate
Anikó Göblös, PhD research fellow
Katalin Bánki Hudákné, laboratory assistant
Györgyné Horváth, laboratory assistant
Andrea Bajkán Tanácsné, laboratory assistant
Éva Dósa-Rácz Viharosné, mathematician

phone number: +36 (62) 545-799, +36 (62) 545-278